آخرین بروز رسانی قیمت ها 1402/12/14 دوشنبه
سبد خرید

(43 )

GPCRs as Therapeutic Targets
GPCR به عنوان اهداف درمانی


کد کتاب: 187746
گارانتی اصالت و سلامت فیزیکی کالا
ارسال رایگان حداقل 40000000
ارسال سریع
موجود
2,059,200 1,648,000

معرفی GPCRs as Therapeutic Targets

GPCRs as Therapeutic Targets

GPCRبه عنوان اهداف درمانی

 

در GPCR ها به عنوان عوامل درمانی، محقق برجسته دکتر آنت گیلکریست، خلاصه ای معتبر و عمیق از حوزه ای پر جنب و جوش و فعال از کشف داروی دانشگاهی و صنعتی ارائه می دهد. این کتاب به عنوان یک مرجع مهم برای محققان جدید و باتجربه ای است که گیرنده های جفت شده با پروتئین G را مطالعه می کنند و در مورد فارماکولوژی مولکولی این کلاس هدف مهم بحث می کند. همچنین شامل مواد به روز در ساختارهای GPCR و طراحی دارویی مبتنی بر ساختار است.

A thorough discussion of the structure, pharmacology, function, and role of G protein-coupled receptors

In GPCRs as Therapeutic Agents, distinguished researcher Dr. Annette Gilchrist delivers an authoritative and in-depth compendium of a vibrant and active area of academic and industrial drug discovery. The book serves as an important reference for new and experienced researchers studying G protein-coupled receptors and discusses the molecular pharmacology of this important target class. It also includes up-to-date material on GPCR structures and structure-based drug design.

The book explores the role of GPCRs in the treatment of disease and novel approaches to their study. In addition to providing information on the structure, pharmacology, and function of GPCRs, it discusses their role in disease states, and advances new methods for measuring GPCR activity in an accessible and engaging way. The book includes:

A thorough introduction to the molecular pharmacology of G protein-coupled receptors, including up-to-date material on GPCR structures and structure-based drug design
In-depth discussions of the evolving pharmacology for GPCRs, intracellular trafficking, and subcellular GPCR signaling
Comprehensive explorations of allosteric modulation, receptor dimerization, deorphanization, and ubiquitination
Fulsome treatments of the role played by GPCRs in the treatments of cancer, substance use disorders, cerebrovascular diseases, and metabolic diseases

Perfect for researchers in biochemistry, cell biology, and pharmacology, GPCRs as Therapeutic Agents will also earn a place in the libraries of professionals working in medicinal chemistry, structural biology, and clinical pharmacology.

Product details

  • Hardback | 1056 pages
  • 167 x 236 x 60mm | 1,952g
  • Wiley-Blackwell
  • Hoboken, United States
  • English
  • Two Volume Set
  • 1119564743
  • 9781119564744
  • 1,551,189